Epitalon
Epithalon / Epithalamin
Telomerase activator — longevity peptide
Anti-AgingLongevitySleep ★ 70
Half-life
Short (~30 min), but biological effects are long-lasting
Cycle
20 day cycles, 2-3 times a year. Not daily year-round.
Storage
Lyophilized: freezer. Reconstituted: 2-8°C, 30 days.
Research
Russian clinical trials, very limited Western trials
About
A Russian peptide that activates the telomerase enzyme and lengthens telomeres. The most-studied longevity peptide.
Mechanism
Increases telomerase activity, preserving telomere length. Also promotes melatonin production.
Dosage
5 mg
1x per day
0102030405060708090100
Draw to 100 units on a U-100 insulin syringe
10 mg · 2 mL BAC
Route
SubQ
Duration
10-20 day cycle
When to take: In the evening before sleep (improves melatonin).
Reconstitution
Vial size (mg): 10 mg · BAC water (mL): 2 mL · Concentration: 5 mg/mL
Use within 30 days after reconstitution.
Benefits
- Telomerase activation
- Improved sleep
- Improved melatonin production
- Antioxidant
- Possible longevity effects (animal data)
- Skin health
Side effects
- Very well tolerated
- No significant side effects reported in trials
Gender notes
Same dose. Popular after age 40.
Cautions
- Pregnancy
- Active cancer (telomerase activation could theoretically stimulate it)
Research
- Khavinson V: Peptides and aging
Neuroendocrinology Letters · 2002
20+ years of research on epitalon and longevity in Russia.
- Khavinson V et al: Epitalon and telomere length
Bulletin of Experimental Biology and Medicine · 2003
Epitalon increases telomerase activity and lengthens telomeres in vitro.