GHK-Cu
Copper Tripeptide-1 (GHK-Cu)
Anti-aging — skin, hair and regeneration
About
A naturally occurring copper-bound tripeptide whose blood levels decline after age 60. Strong evidence for hair growth, wound healing and collagen production.
Mechanism
Binds copper, promoting collagen, elastin and hyaluronic acid production. Modulates expression of 4000+ genes.
Dosage
Draw to 10 units on a U-100 insulin syringe
50 mg · 5 mL BAC
When to take: Any time of day. Topical: best in the evening.
Reconstitution
Vial size (mg): 50 mg · BAC water (mL): 5 mL · Concentration: 10 mg/mL
The solution is blue due to the copper — this is normal.
Benefits
- Promotes hair growth
- Reduces fine lines and wrinkles
- Increases skin thickness
- Wound healing
- Antioxidant
- Anti-inflammatory
Side effects
- Generally very well tolerated
- Mild redness at injection site
- Rare: copper allergy
Gender notes
Cautions
- Copper allergy
- Wilson's disease
- Pregnancy (caution)
Research
- Pickart L, Margolina A: GHK-Cu: A Three-Decade Review
International Journal of Molecular Sciences · 2018
Review of 30 years of GHK-Cu research — gene expression, healing, anti-aging.
- Pickart L: GHK gene modulation
BioMed Research International · 2017
GHK alters expression of more than 4000 genes in human stem cells.